Danger of frustrated sensors: Role of Toll-like receptors and NOD-like receptors in aseptic and septic inflammations around total hip replacements

Danger of frustrated sensors: Role of Toll-like receptors and NOD-like receptors in aseptic and septic inflammations around total hip replacements

The innate immune sensors, Toll-like receptors (TLRs) and nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs), can recognize not only exogenous pathogen-associated molecular patterns (PAMPs), but also endogenous molecules created upon tissue injury, sterile inflammation, and degene...

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Bibliographic Details
Main Authors: Michiaki Takagi, Yuya Takakubo, Jukka Pajarinen, Yasushi Naganuma, Hiroharu Oki, Masahiro Maruyama, Stuart B. Goodman
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Journal of Orthopaedic Translation
Subjects:
innate immune sensors
NLR
TLR
total hip replacement
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X1630273X

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http://www.sciencedirect.com/science/article/pii/S2214031X1630273X

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