Differential effects of excess high-fructose corn syrup on the DNA methylation of hippocampal neurotrophic factor in childhood and adolescence.

Consumption of fructose-containing beverages such as high-fructose corn syrup (HFCS) is increasing, raising concerns about the negative effects of excessive fructose intake. A recent report indicated that excess HFCS intake impairs hippocampal function. In this study, we focused on neurotrophic fact...

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Bibliographic Details
Main Authors: Itsuki Kageyama, Hiroya Yamada, Eiji Munetsuna, Mirai Yamazaki, Yoshitaka Ando, Genki Mizuno, Ryosuke Fujii, Yuki Nouchi, Takuya Wakasugi, Tomohide Sakakibara, Atsushi Teshigawara, Hiroaki Ishikawa, Yohei Shimono, Koji Suzuki, Shuji Hashimoto, Koji Ohashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0270144