Exploring the therapeutic potential of the mitochondrial transfer-associated enzymatic machinery in brain degeneration

Exploring the therapeutic potential of the mitochondrial transfer-associated enzymatic machinery in brain degeneration

Mitochondrial dysfunction is a central event in the pathogenesis of several degenerative brain disorders. It entails fission and fusion dynamics disruption, progressive decline in mitochondrial clearance, and uncontrolled oxidative stress. Many therapeutic strategies have been formulated to reverse...

Full description

Bibliographic Details
Main Authors: Noymar Luque-Campos, Ricardo Riquelme, Luis Molina, Gisela Canedo-Marroquín, Ana María Vega-Letter, Patricia Luz-Crawford, Felipe A. Bustamante-Barrientos
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Physiology
Subjects:
degenerative brain disorders
mitochondrial dysfunction
fission and fusion
mitophagy
oxidative damage
mitochondrial transfer
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1217815/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2023.1217815/full

Similar Items