Diagnostic Yield of 16S Ribosomal Ribonucleic Acid Gene-Based Targeted Metagenomic Sequencing for Evaluation of Pleural Space Infection: A Prospective Study

Diagnostic Yield of 16S Ribosomal Ribonucleic Acid Gene-Based Targeted Metagenomic Sequencing for Evaluation of Pleural Space Infection: A Prospective Study

Objective: To better understand the microbial profile of complicated parapneumonic effusions and empyema, and to evaluate whether antimicrobial selection would differ if guided by targeted metagenomic sequencing (tMGS) vs conventional cultures (CCs) alone. Patients and Methods: We analyzed the pleur...

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Main Authors: Luis Gimenez-Miranda, MD, Bilal F. Samhouri, MD, Matthew J. Wolf, MS, Dagny K. Anderson, MD, David E. Midthun, MD, Kaiser G. Lim, MD, Ryan M. Kern, MD, Robin Patel, MD, Eva M. Carmona, MD, PhD
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Mayo Clinic Proceedings: Innovations, Quality & Outcomes
Online Access:http://www.sciencedirect.com/science/article/pii/S2542454823000498

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http://www.sciencedirect.com/science/article/pii/S2542454823000498

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