The Matrix Stiffness Coordinates the Cell Proliferation and PD-L1 Expression via YAP in Lung Adenocarcinoma

The Matrix Stiffness Coordinates the Cell Proliferation and PD-L1 Expression via YAP in Lung Adenocarcinoma

The extracellular matrix (ECM) exerts physiological activity, facilitates cell-to-cell communication, promotes cell proliferation and metastasis, and provides mechanical support for tumor cells. The development of solid tumors is often associated with increased stiffness. A stiff ECM promotes mechan...

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Bibliographic Details
Main Authors: Yeonhee Park, Dahye Lee, Jeong Eun Lee, Hee Sun Park, Sung Soo Jung, Dongil Park, Da Hyun Kang, Song-I Lee, Seong-Dae Woo, Chaeuk Chung
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cancers
Subjects:
lung adenocarcinoma
matrix stiffness
PD-L1
YAP
Online Access:https://www.mdpi.com/2072-6694/16/3/598

Internet

https://www.mdpi.com/2072-6694/16/3/598

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