Modulation of natural killer cell exhaustion in the lungs: the key components from lung microenvironment and lung tumor microenvironment

Lung cancer is the leading cause of tumor-induced death worldwide and remains a primary global health concern. In homeostasis, due to its unique structure and physiological function, the lung microenvironment is in a state of immune tolerance and suppression, which is beneficial to tumor development...

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Bibliographic Details
Main Authors: Hongxia Zhang, Jian Wang, Fengqi Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1286986/full