Prolonged Hyperoxygenation Treatment Improves Vein Graft Patency and Decreases Macrophage Content in Atherosclerotic Lesions in ApoE3*Leiden Mice

Prolonged Hyperoxygenation Treatment Improves Vein Graft Patency and Decreases Macrophage Content in Atherosclerotic Lesions in ApoE3*Leiden Mice

Unstable atherosclerotic plaques frequently show plaque angiogenesis which increases the chance of rupture and thrombus formation leading to infarctions. Hypoxia plays a role in angiogenesis and inflammation, two processes involved in the pathogenesis of atherosclerosis. We aim to study the effect o...

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Bibliographic Details
Main Authors: Laura Parma, Hendrika A. B. Peters, Fabiana Baganha, Judith C. Sluimer, Margreet R. de Vries, Paul H.A. Quax
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
hyperoxygenation
vein graft disease
atherosclerosis
macrophages
vascular biology
Online Access:https://www.mdpi.com/2073-4409/9/2/336

Internet

https://www.mdpi.com/2073-4409/9/2/336

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