phydms: software for phylogenetic analyses informed by deep mutational scanning
It has recently become possible to experimentally measure the effects of all amino-acid point mutations to proteins using deep mutational scanning. These experimental measurements can inform site-specific phylogenetic substitution models of gene evolution in nature. Here we describe software that ef...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2017-07-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/3657.pdf |