Extracellular Vesicles in Young Serum Contribute to the Restoration of Age-Related Brain Transcriptomes and Cognition in Old Mice

Extracellular Vesicles in Young Serum Contribute to the Restoration of Age-Related Brain Transcriptomes and Cognition in Old Mice

We have previously demonstrated that circulating extracellular vesicles (EVs) are essential to the beneficial effect of young serum on the skeletal muscle regenerative cascade. Here, we show that infusions of young serum significantly improve age-associated memory deficits, and that these effects ar...

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Bibliographic Details
Main Authors: Nicholas F. Fitz, Amrita Sahu, Yi Lu, Fabrisia Ambrosio, Iliya Lefterov, Radosveta Koldamova
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
extracellular vesicles
aging
choroid plexus
hippocampus
memory
klotho
Online Access:https://www.mdpi.com/1422-0067/24/16/12550

Internet

https://www.mdpi.com/1422-0067/24/16/12550

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