Age-Related Decrease in Heat Shock 70-kDa Protein 8 in Cerebrospinal Fluid is Associated with Increased Oxidative Stress
Age-associated declines in protein homeostasis mechanisms (proteostasis) are thought to contribute to age-related neurodegenerative disorders. The increased oxidative stress which occurs with aging can activate a key proteostatic process, chaperone-mediated autophagy. This study investigated age-rel...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2016-07-01
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| Series: | Frontiers in Aging Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnagi.2016.00178/full |