Commentary on human pluripotent stem cell-based blood–brain barrier models

Abstract In 2012, we provided the first published evidence that human pluripotent stem cells could be differentiated to cells exhibiting markers and phenotypes characteristic of the blood–brain barrier (BBB). In the ensuing years, the initial protocols have been refined, and the research community h...

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Bibliographic Details
Main Authors: Ethan S. Lippmann, Samira M. Azarin, Sean P. Palecek, Eric V. Shusta
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12987-020-00222-3