Imputation of spatially-resolved transcriptomes by graph-regularized tensor completion.

High-throughput spatial-transcriptomics RNA sequencing (sptRNA-seq) based on in-situ capturing technologies has recently been developed to spatially resolve transcriptome-wide mRNA expressions mapped to the captured locations in a tissue sample. Due to the low RNA capture efficiency by in-situ captu...

Full description

Bibliographic Details
Main Authors: Zhuliu Li, Tianci Song, Jeongsik Yong, Rui Kuang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-04-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1008218&type=printable