Influence of Sex in the Molecular Characteristics and Outcomes of Malignant Tumors

Influence of Sex in the Molecular Characteristics and Outcomes of Malignant Tumors

BackgroundSex is frequently underestimated as a prognostic biomarker in cancer. In this study, we evaluated a large cohort of patients and public datasets to determine the influence of sex on clinical outcomes, mutational status, and activation of immune pathways in different types of cancer.Methods...

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Main Authors: Jhajaira M. Araujo, Gina Rosas, Carolina Belmar-López, Luis E. Raez, Christian D. Rolfo, Luis J. Schwarz, Ulises Infante-Huaytalla, Kevin J. Paez, Luis R. García, Hober Alvarado, Fany P. Ramos, Sheyla S. Delgado-Espinoza, Jhon B. Cardenas-Farfan, Melanie Cornejo, Daniel Zanabria, Christian Colonio-Cossio, Mario Rojas-Jefferson, Joseph A. Pinto
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Oncology
Subjects:
survival
actionable mutations
sex
GSEA
immune gene sets
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.752918/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.752918/full

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