IFNγ and CTLA-4 Drive Hepatic CD4 T-Cell Tolerance and Protection From Autoimmunity in MiceSummary

IFNγ and CTLA-4 Drive Hepatic CD4 T-Cell Tolerance and Protection From Autoimmunity in MiceSummary

Background & Aims: The liver has a distinct capacity to induce immune tolerance to hepatic antigens. Although liver tolerance can be advantageous for preventing autoimmune and inflammatory diseases, it also can be detrimental by preventing immune surveillance of infected or malignant cells....

Full description

Bibliographic Details
Main Authors: Daria Krzikalla, Alena Laschtowitz, Lisa Leypoldt, Cornelia Gottwick, Pia Averhoff, Sören Weidemann, Ansgar W. Lohse, Samuel Huber, Christoph Schramm, Dorothee Schwinge, Johannes Herkel, Antonella Carambia
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Hepatic Tolerance
Regulatory T Cells
Immune Checkpoints
Co-inhibition
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X23001686

Internet

http://www.sciencedirect.com/science/article/pii/S2352345X23001686

Similar Items