Do distribution volumes and clearances relate to tissue volumes and blood flows? A computer simulation
<p>Abstract</p> <p>Background</p> <p>Kinetics of inhaled agents are often described by physiological models. However, many pharmacokinetic concepts, such as context-sensitive half-times, have been developed for drugs described by classical compartmental models. We deriv...
Main Authors: | Lemmens Hendrikus JM, Hendrickx Jan FA, Shafer Steven L |
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Format: | Article |
Language: | English |
Published: |
BMC
2006-06-01
|
Series: | BMC Anesthesiology |
Online Access: | http://www.biomedcentral.com/1471-2253/6/7 |
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