Tumor treating fields affect mesothelioma cell proliferation by exerting histotype-dependent cell cycle checkpoint activations and transcriptional modulations

Tumor treating fields affect mesothelioma cell proliferation by exerting histotype-dependent cell cycle checkpoint activations and transcriptional modulations

Abstract Although clinical antitumor activity of Tumor Treating Fields (TTFields) has been reported in malignant pleural mesothelioma (MPM) patients, the mechanisms behind the different selectivity displayed by the various MPM histotypes to this physical therapy has not been elucidated yet. Taking a...

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Bibliographic Details
Main Authors: Laura Mannarino, Federica Mirimao, Nicolò Panini, Lara Paracchini, Sergio Marchini, Luca Beltrame, Rosy Amodeo, Federica Grosso, Roberta Libener, Irene De Simone, Giovanni L. Ceresoli, Paolo A. Zucali, Monica Lupi, Maurizio D’Incalci
Format: Article
Language:English
Published: Nature Publishing Group 2022-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05073-4

Internet

https://doi.org/10.1038/s41419-022-05073-4

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