A Novel Strategy for Enhanced Sequestration of Protein-Bound Uremic Toxins Using Smart Hybrid Membranes

A Novel Strategy for Enhanced Sequestration of Protein-Bound Uremic Toxins Using Smart Hybrid Membranes

Currently available hemodialysis (HD) membranes are unable to safely remove protein-bound uremic toxins (PBUTs), especially those bonded to human serum albumin (HSA). To overcome this issue, the prior administration of high doses of HSA competitive binders, such as ibuprofen (IBF), has been proposed...

Full description

Bibliographic Details
Main Authors: Madalena Lopes, Rita F. Pires, Mónica Faria, Vasco D. B. Bonifácio
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Journal of Functional Biomaterials
Subjects:
monophasic hybrid membranes
sol-gel
competitive binding
protein-bound uremic toxins
chronic kidney disease
hemodialysis
Online Access:https://www.mdpi.com/2079-4983/14/3/138

Internet

https://www.mdpi.com/2079-4983/14/3/138

Similar Items