The mammalian circadian clock gene Per2 modulates cell death in response to oxidative stress

The mammalian circadian clock gene Per2 modulates cell death in response to oxidative stress

Living in the earth’s oxygenated environment forced organisms to develop strategies to cope with the damaging effects of molecular oxygen known as reactive oxygen species (ROS). Here we show that Per2, a molecular component of the mammalian circadian clock, is involved in regulating a cell’s respons...

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Bibliographic Details
Main Authors: Maria Chiara Magnone, Sonja eLangmesser, April Candice Bezdek, Tiziano eTallone, Sandro eRusconi, Urs eAlbrecht
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Neurology
Subjects:
Apoptosis
Paraquat
Circadian clock
Bcl-2
adenovirus
p53
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2014.00289/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fneur.2014.00289/full

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