Structural Insights into the Tumor-Promoting Function of the MTDH-SND1 Complex

Structural Insights into the Tumor-Promoting Function of the MTDH-SND1 Complex

Metadherin (MTDH) and Staphylococcal nuclease domain containing 1 (SND1) are overexpressed and interact in diverse cancer types. The structural mechanism of their interaction remains unclear. Here, we determined the high-resolution crystal structure of MTDH-SND1 complex, which reveals an 11-residue...

Full description

Bibliographic Details
Main Authors: Feng Guo, Liling Wan, Aiping Zheng, Vitali Stanevich, Yong Wei, Kenneth A. Satyshur, Minhong Shen, Woojong Lee, Yibin Kang, Yongna Xing
Format: Article
Language:English
Published: Elsevier 2014-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714007098

Internet

http://www.sciencedirect.com/science/article/pii/S2211124714007098

Similar Items