The Effect of Lithium Salt with Ascorbic Acid on the Antioxidant Status and Productivity of Gestating Sows
This research is aimed at the influence of different doses of lithium ascorbate on pigs’ diet estimation, at farrowing sows’ antioxidant status increase, and at lipid peroxidation product level decrease. The research was conducted in farrowing sows of the Irish landrace breed during the second farro...
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MDPI AG
2022-04-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/12/7/915 |
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| author | Konstantin Ostrenko Roman Nekrasov Anastasiya Ovcharova Viktar Lemiasheuski Ivan Kutin |
| author_facet | Konstantin Ostrenko Roman Nekrasov Anastasiya Ovcharova Viktar Lemiasheuski Ivan Kutin |
| author_sort | Konstantin Ostrenko |
| collection | DOAJ |
| description | This research is aimed at the influence of different doses of lithium ascorbate on pigs’ diet estimation, at farrowing sows’ antioxidant status increase, and at lipid peroxidation product level decrease. The research was conducted in farrowing sows of the Irish landrace breed during the second farrow. Three groups of animals were formed, with ten livestock units in each. Thirty days after successful insemination, the sows of the E10, E5 and E2 experimental groups started receiving lithium ascorbate powder together with feed stuff in dosages of 10, 5 and 2 mg/kg of body weight, respectively. Their weighing and biochemical examinations were performed before the substance introduction as well as on the 60th and 110th days of pregnancy. The following were detected in sows’ blood plasma: malondialdehyde, reduced glutathione, oxidized glutathione, SH/SS ratio, superoxide dismutase and glutathione peroxidase activity. Lithium ascorbate usage during sows’ breeding cycle caused a significant increase in SH (reduced glutathione) level by 21% (<i>p</i> < 0.05), SS (oxidized glutathione) level decrease by 17% (<i>p</i> < 0.05), and malondialdehyde level decrease by 60% (<i>p</i> < 0.05). These data outline antioxidant defense system activization, reducing the risk of oxidative stress under the influence of feeding with lithium ascorbate. Lithium ascorbate in dosages of 10 mg/kg per body weight given together with feed stuff shows prominent adaptogene and stress protective features in the most effective way. The research conducted regarding lithium ascorbate usage for farrowing sows can reduce the negative consequences of oxidative stress, increase sows’ health preservation level, and contribute to fertility boost. |
| first_indexed | 2024-03-09T12:10:41Z |
| format | Article |
| id | doaj.art-5be45f55ca68406f9bc75a135d9f0ace |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-09T12:10:41Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-5be45f55ca68406f9bc75a135d9f0ace2023-11-30T22:52:10ZengMDPI AGAnimals2076-26152022-04-0112791510.3390/ani12070915The Effect of Lithium Salt with Ascorbic Acid on the Antioxidant Status and Productivity of Gestating SowsKonstantin Ostrenko0Roman Nekrasov1Anastasiya Ovcharova2Viktar Lemiasheuski3Ivan Kutin4All-Russian Research Institute of Physiology, Biochemistry and Nutrition of Animals—Branch of the L.K. Ernst Federal Research Center for Animal Husbandry, VNIIFBiP, Borovsk 249013, RussiaL.K. Ernst Federal Research Center for Animal Husbandry, Podolsk 142132, Moscow Region, RussiaAll-Russian Research Institute of Physiology, Biochemistry and Nutrition of Animals—Branch of the L.K. Ernst Federal Research Center for Animal Husbandry, VNIIFBiP, Borovsk 249013, RussiaAll-Russian Research Institute of Physiology, Biochemistry and Nutrition of Animals—Branch of the L.K. Ernst Federal Research Center for Animal Husbandry, VNIIFBiP, Borovsk 249013, RussiaAll-Russian Research Institute of Physiology, Biochemistry and Nutrition of Animals—Branch of the L.K. Ernst Federal Research Center for Animal Husbandry, VNIIFBiP, Borovsk 249013, RussiaThis research is aimed at the influence of different doses of lithium ascorbate on pigs’ diet estimation, at farrowing sows’ antioxidant status increase, and at lipid peroxidation product level decrease. The research was conducted in farrowing sows of the Irish landrace breed during the second farrow. Three groups of animals were formed, with ten livestock units in each. Thirty days after successful insemination, the sows of the E10, E5 and E2 experimental groups started receiving lithium ascorbate powder together with feed stuff in dosages of 10, 5 and 2 mg/kg of body weight, respectively. Their weighing and biochemical examinations were performed before the substance introduction as well as on the 60th and 110th days of pregnancy. The following were detected in sows’ blood plasma: malondialdehyde, reduced glutathione, oxidized glutathione, SH/SS ratio, superoxide dismutase and glutathione peroxidase activity. Lithium ascorbate usage during sows’ breeding cycle caused a significant increase in SH (reduced glutathione) level by 21% (<i>p</i> < 0.05), SS (oxidized glutathione) level decrease by 17% (<i>p</i> < 0.05), and malondialdehyde level decrease by 60% (<i>p</i> < 0.05). These data outline antioxidant defense system activization, reducing the risk of oxidative stress under the influence of feeding with lithium ascorbate. Lithium ascorbate in dosages of 10 mg/kg per body weight given together with feed stuff shows prominent adaptogene and stress protective features in the most effective way. The research conducted regarding lithium ascorbate usage for farrowing sows can reduce the negative consequences of oxidative stress, increase sows’ health preservation level, and contribute to fertility boost.https://www.mdpi.com/2076-2615/12/7/915sowslithium ascorbateantioxidant statusglutathione reduction systemoxidative stressproductivity |
| spellingShingle | Konstantin Ostrenko Roman Nekrasov Anastasiya Ovcharova Viktar Lemiasheuski Ivan Kutin The Effect of Lithium Salt with Ascorbic Acid on the Antioxidant Status and Productivity of Gestating Sows Animals sows lithium ascorbate antioxidant status glutathione reduction system oxidative stress productivity |
| title | The Effect of Lithium Salt with Ascorbic Acid on the Antioxidant Status and Productivity of Gestating Sows |
| title_full | The Effect of Lithium Salt with Ascorbic Acid on the Antioxidant Status and Productivity of Gestating Sows |
| title_fullStr | The Effect of Lithium Salt with Ascorbic Acid on the Antioxidant Status and Productivity of Gestating Sows |
| title_full_unstemmed | The Effect of Lithium Salt with Ascorbic Acid on the Antioxidant Status and Productivity of Gestating Sows |
| title_short | The Effect of Lithium Salt with Ascorbic Acid on the Antioxidant Status and Productivity of Gestating Sows |
| title_sort | effect of lithium salt with ascorbic acid on the antioxidant status and productivity of gestating sows |
| topic | sows lithium ascorbate antioxidant status glutathione reduction system oxidative stress productivity |
| url | https://www.mdpi.com/2076-2615/12/7/915 |
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