Longitudinal analysis of DC subsets in patients with ovarian cancer: Implications for immunotherapy

Longitudinal analysis of DC subsets in patients with ovarian cancer: Implications for immunotherapy

BackgroundThe use of circulating cDC1 to generate anti-cancer vaccines is among the most promising approaches to overcome the limited immunogenicity and clinical efficacy of monocyte-derived DC. However, the recurrent lymphopenia and the reduction of DC numbers and functionality in patients with can...

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Bibliographic Details
Main Authors: Beatris Mastelic-Gavillet, Apostolos Sarivalasis, Leyder Elena Lozano, Sebastien Lofek, Tania Wyss, Ignacio Melero, I. Jolanda M. de Vries, Alexandre Harari, Pedro Romero, Lana Elias Kandalaft, Selena Viganó
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
DC
ovarian cancer
cancer vaccine
TLR3
chemotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1119371/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1119371/full

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