Longitudinal bioluminescent imaging of HIV-1 infection during antiretroviral therapy and treatment interruption in humanized mice.

Longitudinal bioluminescent imaging of HIV-1 infection during antiretroviral therapy and treatment interruption in humanized mice.

Non-invasive bioluminescent imaging (NIBLI) of HIV-1 infection dynamics allows for real-time monitoring of viral spread and the localization of infected cell populations in living animals. In this report, we describe full-length replication-competent GFP and Nanoluciferase (Nluc) expressing HIV-1 re...

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Bibliographic Details
Main Authors: John D Ventura, Jagadish Beloor, Edward Allen, Tongyu Zhang, Kelsey A Haugh, Pradeep D Uchil, Christina Ochsenbauer, Collin Kieffer, Priti Kumar, Thomas J Hope, Walther Mothes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008161

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https://doi.org/10.1371/journal.ppat.1008161

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