Mitochondrial calcium uniporter activity is dispensable for MDA-MB-231 breast carcinoma cell survival.

Calcium uptake through the mitochondrial Ca2+ uniporter (MCU) is thought to be essential in regulating cellular signaling events, energy status, and survival. Functional dissection of the uniporter is now possible through the recent identification of the genes encoding for MCU protein complex subuni...

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Bibliographic Details
Main Authors: Duane D Hall, Yuejin Wu, Frederick E Domann, Douglas R Spitz, Mark E Anderson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4011874?pdf=render