Mitochondrial calcium uniporter activity is dispensable for MDA-MB-231 breast carcinoma cell survival.
Calcium uptake through the mitochondrial Ca2+ uniporter (MCU) is thought to be essential in regulating cellular signaling events, energy status, and survival. Functional dissection of the uniporter is now possible through the recent identification of the genes encoding for MCU protein complex subuni...
Main Authors: | Duane D Hall, Yuejin Wu, Frederick E Domann, Douglas R Spitz, Mark E Anderson |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4011874?pdf=render |
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