Bile acid-mediated signaling in cholestatic liver diseases

Abstract Chronic cholestatic liver diseases, such as primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC), are associated with bile stasis and gradually progress to fibrosis, cirrhosis, and liver failure, which requires liver transplantation. Although ursodeoxycholic acid is ef...

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Bibliographic Details
Main Authors: Jing Zeng, Jiangao Fan, Huiping Zhou
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-023-01035-1