Formulation and Evaluation of Amikacin Sulfate Loaded Dextran Nanoparticles against Human Pathogenic Bacteria

Formulation and Evaluation of Amikacin Sulfate Loaded Dextran Nanoparticles against Human Pathogenic Bacteria

Amikacin sulfate-loaded dextran sulfate sodium nanoparticles were formulated, lyophilized (LADNP), and then analyzed. The LADNP had a −20.9 ± 8.35 mV zeta potential, PDI of 0.256, and % PDI of 67.7. The zeta average nano size of LADNP was 317.9 z. d.nm, while the dimension of an individual particle...

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Bibliographic Details
Main Authors: Rahamat Unissa Syed, Sivakumar S. Moni, Muhammad Nawaz, Mohammed Khaled Bin Break, Nasrin E. Khalifa, Siddig Ibrahim Abdelwahab, Reham Meshal Alharbi, Raghad Huraid Alfaisal, Bayan Naif Al Basher, Entsar Mohammed Alhaidan
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Pharmaceutics
Subjects:
dextran sulfate sodium
Amikacin
Nanoparticles
physical characterization
antibacterial effect
human pathogenic bacteria
Online Access:https://www.mdpi.com/1999-4923/15/4/1082

Internet

https://www.mdpi.com/1999-4923/15/4/1082

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