A high-speed search engine pLink 2 with systematic evaluation for proteome-scale identification of cross-linked peptides

A high-speed search engine pLink 2 with systematic evaluation for proteome-scale identification of cross-linked peptides

The identification of cross-linked peptides at a proteome scale for interactome analyses represents a complex challenge. Here the authors report an efficient and reliable search engine pLink 2 for proteome-scale cross-linking mass spectrometry analyses, and demonstrate how to systematically evaluate...

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Bibliographic Details
Main Authors: Zhen-Lin Chen, Jia-Ming Meng, Yong Cao, Ji-Li Yin, Run-Qian Fang, Sheng-Bo Fan, Chao Liu, Wen-Feng Zeng, Yue-He Ding, Dan Tan, Long Wu, Wen-Jing Zhou, Hao Chi, Rui-Xiang Sun, Meng-Qiu Dong, Si-Min He
Format: Article
Language:English
Published: Nature Portfolio 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11337-z

Internet

https://doi.org/10.1038/s41467-019-11337-z

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