The role of estrogen receptors (ERs)-Notch pathway in thyroid toxicity induced by Di-2-ethylhexyl phthalate (DEHP) exposure: Population data and in vitro studies

The role of estrogen receptors (ERs)-Notch pathway in thyroid toxicity induced by Di-2-ethylhexyl phthalate (DEHP) exposure: Population data and in vitro studies

Background: This study aimed to assess the exposure level and risk of Di-2-ethylhexyl Phthalate (DEHP) among adults in Jilin Province, China, clarify the impact of DEHP on human thyroid function, and to explore the role of estrogen receptors (ERs)-Notch signaling pathway in the effect of DEHP metabo...

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Bibliographic Details
Main Authors: Xueting Zhang, Yuezhu Zhang, Xin Feng, Haotang Zhao, Hui Ye, Xiaoqi Fang, Jianwei Cui, Wen Qi, Lin Ye
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
DEHP metabolites
Risk assessment
Estrogen receptor
Notch
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323012319

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http://www.sciencedirect.com/science/article/pii/S0147651323012319

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