Notch1 signaling induces epithelial-mesenchymal transition in lens epithelium cells during hypoxia

Abstract Background Posterior Capsular Opacification (PCO) is one of the most common complications of cataract surgery which can result in severe visual damage. Epithelial-Mesenchymal Transition (EMT) of lens epithelium cells (LEC) is the pathological basis of PCO. Recent research showed that hypoxi...

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Bibliographic Details
Main Authors: Lei Liu, Wei Xiao
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Ophthalmology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12886-017-0532-1