Isolation and Characterization of Two Novel Colorectal Cancer Cell Lines, Containing a Subpopulation with Potential Stem-Like Properties: Treatment Options by MYC/NMYC Inhibition

Isolation and Characterization of Two Novel Colorectal Cancer Cell Lines, Containing a Subpopulation with Potential Stem-Like Properties: Treatment Options by MYC/NMYC Inhibition

Cancer stem cells (CSC) are crucial mediators of cancer relapse. Here, we isolated two primary human colorectal cancer cell lines derived from a rectal neuroendocrine carcinoma (BKZ-2) and a colorectal adenocarcinoma (BKZ-3), both containing subpopulations with potential stem-like properties. Protei...

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Bibliographic Details
Main Authors: Jan Schulte am Esch, Beatrice Ariane Windmöller, Johannes Hanewinkel, Jonathan Storm, Christine Förster, Ludwig Wilkens, Martin Krüger, Barbara Kaltschmidt, Christian Kaltschmidt
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
colorectal cancer stem cells
NMYC
MYC
ATRA
EMT
KJ-Pyr-9
Online Access:https://www.mdpi.com/2072-6694/12/9/2582

Internet

https://www.mdpi.com/2072-6694/12/9/2582

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