Effect of intermittent subchronic MK‐801 administration on dopamine synthesis capacity and responsiveness in the prefrontal cortex

Effect of intermittent subchronic MK‐801 administration on dopamine synthesis capacity and responsiveness in the prefrontal cortex

Abstract Aim The therapeutic potential of N‐methyl‐D‐aspartate glutamate receptor (NMDAR) antagonists, particularly ketamine, in mood disorders, is linked to their modulation of dopamine dynamics in the medial prefrontal cortex (mPFC). However, conflicting effects of distinct NMDAR antagonists, like...

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Bibliographic Details
Main Authors: Kazuro Shibata, Kosuke Enomoto, Takahiro Tsutsumi, Hiroyuki Muraoka, Tatsu Fuwa, Masahiko Kawano, Jun Ishigooka, Ken Inada, Katsuji Nishimura, Hidehiro Oshibuchi
Format: Article
Language:English
Published: Wiley 2024-06-01
Series:Neuropsychopharmacology Reports
Subjects:
dopamine
medial prefrontal cortex
MK‐801
NMDAR antagonists
subchronic
Online Access:https://doi.org/10.1002/npr2.12420

Internet

https://doi.org/10.1002/npr2.12420

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