Single-Cell Transcriptomics Uncovers Cellular Heterogeneity, Mechanisms, and Therapeutic Targets for Parkinson’s Disease

Single-Cell Transcriptomics Uncovers Cellular Heterogeneity, Mechanisms, and Therapeutic Targets for Parkinson’s Disease

Objective: This study aimed to exploit cellular heterogeneity for revealing mechanisms and identifying therapeutic targets for Parkinson’s disease (PD) via single-cell transcriptomics.Methods: Single-cell RNA sequencing (scRNA-seq) data on midbrain specimens from PD and healthy individuals were obta...

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Bibliographic Details
Main Authors: Jianjun Huang, Li Liu, Lingling Qin, Hehua Huang, Xue Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Genetics
Subjects:
Parkinson’s disease
single-cell RNA sequencing
cellular heterogeneity
molecular mechanisms
therapeutic targets
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.686739/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.686739/full

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