Targeted Hybridization Capture of SARS-CoV-2 and Metagenomics Enables Genetic Variant Discovery and Nasal Microbiome Insights

Targeted Hybridization Capture of SARS-CoV-2 and Metagenomics Enables Genetic Variant Discovery and Nasal Microbiome Insights

ABSTRACT The emergence of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genetic variants that may alter viral fitness highlights the urgency of widespread next-generation sequencing (NGS) surveillance. To profile genetic variants of the entire SARS-CoV-2 genome, we developed and...

Full description

Bibliographic Details
Main Authors: Dorottya Nagy-Szakal, Mara Couto-Rodriguez, Heather L. Wells, Joseph E. Barrows, Marilyne Debieu, Kristin Butcher, Siyuan Chen, Agnes Berki, Courteny Hager, Robert J. Boorstein, Mariah K. Taylor, Colleen B. Jonsson, Christopher E. Mason, Niamh B. O’Hara
Format: Article
Language:English
Published: American Society for Microbiology 2021-10-01
Series:Microbiology Spectrum
Subjects:
COVID-19
SARS-CoV-2
infectious disease
microbiome
next-generation sequencing
viral genomics
Online Access:https://journals.asm.org/doi/10.1128/Spectrum.00197-21

Internet

https://journals.asm.org/doi/10.1128/Spectrum.00197-21

Similar Items