Aryl hydrocarbon receptor nuclear translocator limits the recruitment and function of regulatory neutrophils against colorectal cancer by regulating the gut microbiota

Aryl hydrocarbon receptor nuclear translocator limits the recruitment and function of regulatory neutrophils against colorectal cancer by regulating the gut microbiota

Abstract Background Although the role and mechanism of neutrophils in tumors have been widely studied, the precise effects of aryl hydrocarbon receptor nuclear translocator (ARNT) on neutrophils remain unclear. In this study, we investigated the roles of ARNT in the function of CD11b+Gr1+ neutrophil...

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Bibliographic Details
Main Authors: Yujing Bi, Qiuli Yang, Zhengchao Li, Yuexin Wang, Yufei Wang, Anna Jia, Zhiyuan Pan, Ruifu Yang, Guangwei Liu
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Tumor-associated neutrophils
ARNT, gut microbiota
Immune microenvironment
Colorectal cancer
microbiota
Online Access:https://doi.org/10.1186/s13046-023-02627-y

Internet

https://doi.org/10.1186/s13046-023-02627-y

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