Imiquimod-induced pruritus in female wild-type and knockin Wistar rats: underscoring behavioral scratching in a rat model for antipruritic treatments

Abstract Objectives Animal models of skin disease are used to evaluate therapeutics to alleviate disease. One common clinical dermatological complaint is pruritus (itch), but there is a lack of standardization in the characterization of pre-clinical models and scratching behavior, a key itch endpoin...

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Bibliographic Details
Main Authors: Karen Lariosa-Willingham, Dmitri Leonoudakis, Florian Simon, Kendall Walker, Philippe Guillaume, Liling Warren, Jennifer Stratton
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Research Notes
Subjects:
Online Access:https://doi.org/10.1186/s13104-023-06627-1