A history of childhood maltreatment is associated with altered DNA methylation levels of DNA methyltransferase 1 in maternal but not neonatal mononuclear immune cells

A history of childhood maltreatment is associated with altered DNA methylation levels of DNA methyltransferase 1 in maternal but not neonatal mononuclear immune cells

Childhood maltreatment (CM) is associated with alterations in DNA methylation (DNAm) especially in stress response genes. Due to the higher risk of overall health complications of individuals with a parental history of CM, intergenerational transmission of CM-associated DNAm changes has been investi...

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Bibliographic Details
Main Authors: Rezan Nehir Mavioglu, Laura Ramo-Fernandez, Anja M. Gumpp, Iris-Tatjana Kolassa, Alexander Karabatsiakis
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Psychiatry
Subjects:
childhood maltreatment
early life adversity
DNA methylation
intergenerational transmission
DNMT1
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2022.945343/full

Internet

https://www.frontiersin.org/articles/10.3389/fpsyt.2022.945343/full

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