Distribution Evaluation of Tenofovir in the Breast Milk of Mothers With HBeAg-Positive Chronic HBV Infection After Treatment With Tenofovir Alafenamide and Tenofovir Disoproxil Fumarate by a Sensitive UPLC-MS/MS Method

Distribution Evaluation of Tenofovir in the Breast Milk of Mothers With HBeAg-Positive Chronic HBV Infection After Treatment With Tenofovir Alafenamide and Tenofovir Disoproxil Fumarate by a Sensitive UPLC-MS/MS Method

Tenofovir alafenamide (TAF) is a novel prodrug of tenofovir (TFV) that has been approved for the treatment of chronic hepatitis B virus (HBV) infection. It has greater plasma stability and more favorable renal safety than tenofovir disoproxil fumarate (TDF), the first approved oral prodrug of TFV. H...

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Bibliographic Details
Main Authors: Na Yang, Guanlun Zhou, Xiaoliang Cheng, Jun He, Yan Chen, Chao Chen, Meijuan Li, Jiajia Ge, Min Wang, Tianqi Zhang, Weihong Ge, Huaijun Zhu, Guorong Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Pharmacology
Subjects:
tenofovir alafenamide
tenofovir
breast milk
UPLC—MS /MS
HBV
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.734760/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.734760/full

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