Waste Clearance in the Brain and Neuroinflammation: A Novel Perspective on Biomarker and Drug Target Discovery in Alzheimer’s Disease

Alzheimer’s disease (AD) is a multifactorial disease with a heterogeneous etiology. The pathology of Alzheimer’s disease is characterized by amyloid-beta and hyperphosphorylated tau, which are necessary for disease progression. Many clinical trials on disease-modifying drugs for AD have failed to in...

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Bibliographic Details
Main Author: Kazuhiko Uchida
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/5/919