O-Mannosylation of Proteins Enables <italic toggle="yes">Histoplasma</italic> Yeast Survival at Mammalian Body Temperatures
ABSTRACT The ability to grow at mammalian body temperatures is critical for pathogen infection of humans. For the thermally dimorphic fungal pathogen Histoplasma capsulatum, elevated temperature is required for differentiation of mycelia or conidia into yeast cells, a step critical for invasion and...
Main Authors: | Andrew L. Garfoot, Kristie D. Goughenour, Marcel Wüthrich, Murugesan V. S. Rajaram, Larry S. Schlesinger, Bruce S. Klein, Chad A. Rappleye |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2018-03-01
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Series: | mBio |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mBio.02121-17 |
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