Nck1 Deficiency Impairs Adipogenesis by Activation of PDGFRα in Preadipocytes
Summary: Obesity results from an excessive expansion of white adipose tissue (WAT), which is still poorly understood from an etiologic-mechanistic perspective. Here, we report that Nck1, a Src homology domain-containing adaptor, is upregulated during WAT expansion and in vitro adipogenesis. In agree...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-08-01
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Series: | iScience |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004218300981 |