Nck1 Deficiency Impairs Adipogenesis by Activation of PDGFRα in Preadipocytes

Summary: Obesity results from an excessive expansion of white adipose tissue (WAT), which is still poorly understood from an etiologic-mechanistic perspective. Here, we report that Nck1, a Src homology domain-containing adaptor, is upregulated during WAT expansion and in vitro adipogenesis. In agree...

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Bibliographic Details
Main Authors: Nida Haider, Julie Dusseault, Louise Larose
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004218300981