Injectable pH-responsive hydrogel for combinatorial chemoimmunotherapy tailored to the tumor microenvironment

Injectable pH-responsive hydrogel for combinatorial chemoimmunotherapy tailored to the tumor microenvironment

Abstract Although combination chemoimmunotherapy shows promising clinical results for cancer treatment, this approach is largely restricted by variable objective response rate and severe systemic adverse effects of immunotherapeutic antibody and chemotherapeutic drugs. Therefore, an in situ-formed t...

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Bibliographic Details
Main Authors: Jun Gu, Gang Zhao, Jiangkun Yu, Pei Xu, Jiabin Yan, Zhengshuai Jin, Sheng Chen, Yong Wang, Leshuai W. Zhang, Yangyun Wang
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Journal of Nanobiotechnology
Subjects:
Injectable hydrogel
pH-responsive
Silk-chitosan composite
Chemoimmunotherapy
Tumor microenvironment
Online Access:https://doi.org/10.1186/s12951-022-01561-z

Internet

https://doi.org/10.1186/s12951-022-01561-z

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