Acute retigabine‐induced effects on myelinated motor axons in amyotrophic lateral sclerosis

Abstract Altered motor neuron excitability in patients with amyotrophic lateral sclerosis (ALS) has been suggested to be an early pathophysiological mechanism associated with motor neuron death. Compounds that affect membrane excitability may therefore have disease‐modifying effects. Through which m...

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Bibliographic Details
Main Authors: Boudewijn T. H. M. Sleutjes, Diederik J. L. Stikvoort García, Maria O. Kovalchuk, Jules A. A. C. Heuberger, Geert Jan Groeneveld, Hessel Franssen, Leonard H. van denBerg
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:Pharmacology Research & Perspectives
Subjects:
Online Access:https://doi.org/10.1002/prp2.983