First Identification of 12β-Deoxygonyautoxin 5 (12α-Gonyautoxinol 5) in the Cyanobacterium <i>Dolichospermum circinale</i> (TA04) and 12β-Deoxysaxitoxin (12α-Saxitoxinol) in <i>D. circinale</i> (TA04) and the Dinoflagellate <i>Alexandrium pacificum</i> (Group IV) (120518KureAC)

First Identification of 12β-Deoxygonyautoxin 5 (12α-Gonyautoxinol 5) in the Cyanobacterium <i>Dolichospermum circinale</i> (TA04) and 12β-Deoxysaxitoxin (12α-Saxitoxinol) in <i>D. circinale</i> (TA04) and the Dinoflagellate <i>Alexandrium pacificum</i> (Group IV) (120518KureAC)

Saxitoxin and its analogues, paralytic shellfish toxins (PSTs), are potent and specific voltage-gated sodium channel blockers. These toxins are produced by some species of freshwater cyanobacteria and marine dinoflagellates. We previously identified several biosynthetic intermediates of PSTs, as wel...

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Bibliographic Details
Main Authors: Michiru Akamatsu, Ryosuke Hirozumi, Yuko Cho, Yuta Kudo, Keiichi Konoki, Yasukatsu Oshima, Mari Yotsu-Yamashita
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Marine Drugs
Subjects:
saxitoxin
<i>Dolichospermum circinale</i>
<i>Alexandrium pacificum</i>
paralytic shellfish toxins
12β-deoxygonyautoxin 5 (12α-gonyautoxinol 5)
12β-deoxysaxitoxin (12α-saxitoxinol)
Online Access:https://www.mdpi.com/1660-3397/20/3/166

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