Peptide Loading on MHC Class I Molecules of Tumor Cells
MHC class I molecules present peptides to cytotoxic T cells allowing the immune system to scan for intracellular pathogens and mutated proteins. The generation of antigenic peptides is a multistep process that ends in the endoplasmic reticulum (ER). Only peptides with the right length and sequence w...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Bio-protocol LLC
2016-09-01
|
Series: | Bio-Protocol |
Online Access: | https://bio-protocol.org/en/bpdetail?id=1932&type=0 |