Peptide Loading on MHC Class I Molecules of Tumor Cells

MHC class I molecules present peptides to cytotoxic T cells allowing the immune system to scan for intracellular pathogens and mutated proteins. The generation of antigenic peptides is a multistep process that ends in the endoplasmic reticulum (ER). Only peptides with the right length and sequence w...

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Bibliographic Details
Main Authors: Loredana Cifaldi, Franco Locatelli, Doriana Fruci
Format: Article
Language:English
Published: Bio-protocol LLC 2016-09-01
Series:Bio-Protocol
Online Access:https://bio-protocol.org/en/bpdetail?id=1932&type=0