Peptide Loading on MHC Class I Molecules of Tumor Cells

MHC class I molecules present peptides to cytotoxic T cells allowing the immune system to scan for intracellular pathogens and mutated proteins. The generation of antigenic peptides is a multistep process that ends in the endoplasmic reticulum (ER). Only peptides with the right length and sequence w...

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Hlavní autoři: Loredana Cifaldi, Franco Locatelli, Doriana Fruci
Médium: Článek
Jazyk:English
Vydáno: Bio-protocol LLC 2016-09-01
Edice:Bio-Protocol
On-line přístup:https://bio-protocol.org/en/bpdetail?id=1932&type=0