PrPC from stem cells to cancer

PrPC from stem cells to cancer

The cellular prion protein PrPC was initially discovered as the normal counterpart of the pathological scrapie prion protein PrPSc, the main component of the infectious agent of Transmissible Spongiform Encephalopathies. While clues as to the physiological function of this ubiquitous protein were gr...

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Bibliographic Details
Main Authors: Séverine eMartin-Lannerée, Théo Z Hirsch, Julia eHernandez-Rapp, Sophie eHalliez, Jean-Luc eVilotte, Jean-Marie eLaunay, Sophie eMouillet-Richard
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Cancer
stem cell
self-renewal
cellular prion protein
cell fate specification
prion infection
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2014.00055/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcell.2014.00055/full

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