Does the trained immune system play an important role in the extreme longevity that is seen in the Sardinian blue zone?

Villages in the island of Sardinia in the Mediterranean that display exceptional longevity are clustered within a defined mountainous region. Because of their unique location we hypothesize that these villages had a unique infectious disease exposure relevant to the observed successful longevity. Th...

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Bibliographic Details
Main Authors: Mark J. Soloski, Michel Poulain, Giovanni M. Pes
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Aging
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2022.1069415/full