Analysis of AT7519 as a pro-resolution compound in an acetaminophen-induced mouse model of acute inflammation by UPLC-MS/MS
Abstract Background Uncontrolled inflammation contributes to the progression of organ damage in acute conditions, such as acetaminophen-induced acute liver injury (APAP-ALI) and there are limited treatments for this condition. AT7519, a cyclic-dependent kinase inhibitor (CDKI), has been used success...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-06-01
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Series: | Journal of Inflammation |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12950-023-00345-y |