Transcriptome sequencing and microRNA–mRNA regulatory network construction in the lens from a Na2SeO3-induced Sprague Dawley rat cataract model

Abstract Background A sight-threatening, cataract is a common degenerative disease of the ocular lens. This study aimed to explore the regulatory mechanism of age-related cataract (ARC) formation and progression. Methods Cataracts in Sprague Dawley rats were induced by adopting the method that injec...

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Bibliographic Details
Main Authors: Rui Fang, Pei-Lin Yue, Hai-Long Li, Xue-Fei Ding, Yu-Xuan Jia, Zhao-Chuan Liu, Hong-Gang Zhou, Xu-Dong Song
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Ophthalmology
Subjects:
Online Access:https://doi.org/10.1186/s12886-023-03202-x