A randomised crossover trial of tezacaftor-ivacaftor for gut dysfunction in cystic fibrosis with magnetic resonance imaging (MRI) outcomes: a pilot study. [version 2; peer review: 2 approved]

A randomised crossover trial of tezacaftor-ivacaftor for gut dysfunction in cystic fibrosis with magnetic resonance imaging (MRI) outcomes: a pilot study. [version 2; peer review: 2 approved]

Background People with cystic fibrosis (CF) can experience recurrent chest infections, pancreatic exocrine insufficiency and gastrointestinal symptoms. New cystic fibrosis transmembrane conductance regulator (CFTR) modulator drugs improve lung function but gastrointestinal effects are unclear. We ai...

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Detalhes bibliográficos
Principais autores: Christabella Ng, Helen Barr, Caroline Hoad, Neele S Dellschaft, Robin Spiller, Luca Marciani, Alan R Smyth, Trevor Hill, Colin Crooks, Jochen G Mainz, Alex Menys, Giles Major, Penny A. Gowland
Formato: Artigo
Idioma:English
Publicado em: F1000 Research Ltd 2024-03-01
coleção:NIHR Open Research
Assuntos:
cystic fibrosis
gastrointestinal symptoms
CFTR modulators
magnetic resonance imaging.
eng
Acesso em linha:https://openresearch.nihr.ac.uk/articles/3-65/v2

Internet

https://openresearch.nihr.ac.uk/articles/3-65/v2

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